|
Home
Informationen für Studenten
Fortbildung
Wissenschaftliche
Aktivitäten
Projekte
Personal
Publikationen
Links
| |
Ausgewählte Publikationen der Abteilung zu thematischen
Schwerpunkten
Endokrine Disruptoren
Wuttke
W, Jarry H, Seidlova-Wuttke D.
Definition, classification and mechanism of action of endocrine disrupting
chemicals. Hormones (Athens) 9:9-15.
Schlecht C, Klammer H,
Frauendorf H, Wuttke W, Jarry H.
Pharmacokinetics and metabolism of benzophenone 2 in the
rat. Toxicology.
2008 Mar 12;245(1-2):11-7
H. Jarry, C. Schlecht, H.
Klammer, W. Wuttke
Praktische Bedeutung von endokrin aktiven Chemikalien. Internistische Praxis
(2008/ Folge 1), Hans Marseille Verlag GmbH München
C. Schmutzler et al.,
Endocrine disruptors and the Thyroid Gland-A combined in Vitro and in Vivo
Analysis of Potential New Biomarkers. Environmental health Perspectives,
Dezember 2007, Vol. 115, Supplement 1, P 77-83
Schmutzler C, Bacinski A,
Gotthardt I, Huhne K, Armbrugger P, Klammer H, Schlecht, C.,.
The UV filter benzophenone 2 interfeers with the thyroid hormone axis in the rat
and is a potent in vitro inhibitor of human recombinant thyroid peroxidase,
Endocrinology,148(6):2835-44, 2007
Klammer H, Schlecht C, Wuttke W, Schmutzler C, Gotthardt I,
Kohrle J, Jarry H
Effects of a 5-day treatment with the UV-filter octyl,ethoxycinnamate (OMC) on
the function of the hypothalamo-pituitary-thyroid function in rats. Toxicology,
238(2-3): 192-9, 2007
Wolfgang Wuttke
Multi-organic risk assessment of selected endocrine disruptors,
www.credocluster.info , (Nov. 2006), page 5-6
Jarry, H., Christoffel, J., Rimoldi, G., Koch,
L,
Wuttke, W.
Multi-organic endocrine disrupting activity of the UV screen
benzophenone 2 (BP2) in ovariectomized adult rats after 5 days treatment,
Toxicology, 205: 87-93, 2004
Seidlová-Wuttke, D., Jarry, H.,
Wuttke, W.
Pure estrogenic effect of benzophenone-2 (BP2) but not of bisphenol A
(BPA) and dibutylphtalate (DBP)in uterus, vagina and bone, Toxicology,
205: 103-112, 2004
Schlecht, C., Klammer, H., Jarry, H.,
Wuttke, W.
Effects of estradiol,
benzophenone-2 and benzophenone-3 on the expression pattern of the estrogen
receptors (ER) alpha and beta, the estrogen receptor-related receptor 1 (ERR1)
and the aryl hydrocarbon receptor (AhR) in adult ovariectomized rats,
Toxicology, 205: 123-130, 2004
Jarry, H.,
Gamer A.,
Wuttke W.
Effects of 5-day styrene
inhalation on serum LH and testosterone levels and on hypothalamic and striatal
aminoacid neurotransmitter concentrations in male rats.
Inhalation
Toxicology,
16:209-215, 2004
Schlumpf, M.,
Jarry, H., Wuttke, W., Ma, R., Lichtensteiger, W.
Estrogenic activity and estrogen receptor ß binding of the UV filter
3-benzylidene camphor. Comparison with 4-methylbenzylidene camphor.
Toxicology 199:109-120, 2004
Schlumpf M.,
Schmid, P., Durrer, S., Conscience, M., Maerkel, K., Henseler, M., Gruetter, M.,
Herzog, I., Reolon, S., Ceccatelli, R., Faass, O., Stutz, E., Jarry, H., Wuttke,
W., Lichtensteiger, W.
Endocrine activity and developmental toxicity of cosmetic UV filters – an
update. Toxicology 205:113-122, 2004
Schmutzler, C.,
Hamann, I., Hofmann, P.J., Kovacs, G., Stemmler, L., Mentrup, B., Schomburg, L.,
Ambrugger, P., Grüters, A., Seidlova-Wuttke, D., Jarry, H., Wuttke, W, Köhrle,
J.
Endocrine active compounds affect thyrotropin and thyroid hormone levels in
serum as well as endpoints of thyroid hormone action in liver, heart and kidney. Toxicology 205:95-102, 2004
Wuttke, W.,
Jarry, H., Becker, T., Schultens, A., Christoffel, V., Gorkow, C.,
Seidlová-Wuttke, D.
Phytoestrogens: Endocrine disrupters or replacement for hormone replacement
therapy? Maturitas 44:S9-20, 2003
Pflanzliche Extrakte
Kapur P, Wuttke W, Seidlova-Wuttke D
The Cimicifuga
racemosa special extract BNO 1055 prevents hot flashes in ovariectomized rats.
Phytomedicine 2010 17:890-894
Kelly LA, O’Leary JJ, Seidlova-Wuttke D, Wuttke W, Norris LA.
Genistein alters coagulation gene expression in ovarietomised rats treated with
phytoestrogens. Thrombosis and Haemostasis 2010
Ehrhard C, Wessels JT, Wuttke
W, Seidlova-Wuttke D.
The effects of 20-OH-Ecdysone and 17ß-Estradiol in the skin of ovariectomized
rats. Menopause 2010.
Seidlova-Wuttke
D, Christel D, Kapur P, Nguyen BT, Jarry H, Wuttke W.
Beta-Ecdysone has bone protective but no estrogenic effects in ovariectomized
rats. Phytomedicine. June 2010. [Epub ahead of print]
Stuermer
EK, Sehmisch S, Rack T, Wenda E, Seidlova-Wuttke D, Tezval M, Wuttke W, Frosch
KH, Stuermer KM.
Estrogen and raloxifene
improve metaphyseal fracture healing in the early phase of osteoporosis. A new
fracture-healing model at the tibia in rat. Langenbecks Arch Surg.
2010 Feb; 395(2):163-72.
Kolios
L, Hoerster AK, Sehmisch S, Malcherek MC, Rack T, Tezval M, Seidlova-Wuttke D,
Wuttke W, Stuermer KM, Stuermer EK.
Do estrogen and
alendronate improve metaphyseal fracture healing when applied as osteoporosis
prophylaxis? Calcif Tissue Int. 2010 Jan;86(1):23-32.
Kolios
L, Schumann J, Sehmisch S, Rack T, Tezval M, Seidlova-Wuttke D, Frosch, KH,
Stuermer K, Stuermer E.
Effects of Black Cohosh
(Cimicifuga racemosa) and Estrogen on
Metaphyseal Fracture Healing in the Early Stage of Osteoporosis in
Ovariectomized Rats. Planta Med. 2010 Jan 26 (Epub ahead of print)
Kapur
P, Wuttke W, Seidlova-Wuttke D (2010)
Beneficial effects of ß-Ecdysone on joint, epiphyseal cartilage tissue and
trabecular bone in ovarectomized rats. Phytomedicine, 17: 350-355
Seidlová-Wuttke
D, Ehrhardt C, Wuttke W
(2010): Metabolic effects of 20-OH
Ecdysone in ovarectomized rats.
J of Steroid
Biochem Mol Biol 119, (3-5): 121-126
Thielemann A,
Wuttke W, Wuttke M, Seidlova-Wuttke D
(2010): Comparison of urodynamic effects
of phytoestrogens equol , puerarin and genistein with these of 17beta in
ovariectomiezed rats.
Exp Gerontol. 45(2)
129-137
Wuttke
W, Jarry H, Seidlova-Wuttke D.
Plant derived alternative treatments for the ageing male: facts and myths.
Ageing Male 13:75-81
Seidlova-Wuttke
D, Jarry H, Wuttke W (2009): Effects of Estradiolbenzoat
(EB), Raloxifen
(Ral) and an ethanolic extract of
Cimicifuga racemosa
(CR) in non classical estrogen regulated
organs of ovariectomized rats. Planta Medica, 75, 1279-1285.
Dana
Seidlova-Wuttke, Hubertus Jarry, Wolfgang Wuttke
Effects
of Estradiolbenzoat (EB), Raloxifen (Ral) and an ethanolic extract of Cimicifuga
racemosa (CR) in non classical estrogen regulated organs of ovariectomized rats. Planta Medica, 2009; 75: 1-7
Rachoń
D, Menche A, Vortherms T, Seidlová-Wuttke D, Wuttke W.
Effects of dietary equol
administration on the mammary gland in ovariectomized Sprague-Dawley rats. Menopause.
2008 Mar-Apr;15(2):340
Dominik Rachon, Tina
Vortherms, Dana Seidlová-Wuttke, Wolfgang Wuttke
Effects of black cohosh extract on body weight gain, intra-abdominal fat
accumulation, plasma lipids and glucose tolerance in ovariectomized
Sprague–Dawley rats. Maturitas 60 (2008) 209–215
Rachoń
D, Vortherms T, Seidlová-Wuttke D, Jarry H, Wuttke W.
Dietary quercetin does
not affect pituitary lutenizing hormone (LH) expression and has no uterotropic
effects in ovariectomized Sprague-Dawley rats. Food Chem Toxicol. 2008 Feb;46(2):513-8. Epub 2007 Aug 29
W. Wuttke et al.,(NIH)
Safety and Benefit of Black cohosh (BC workshop manual), subm. to Nutrition
Today, 2008
W.
Wuttke, H. Jarry, D. Seidlová-Wuttke, T. Devyatchenko, O. Pogodin,
S.A. Levenets
Extrakte aus Mönchspfeffer (Vitex Agnus castus) Stellenwert der Therapie in der
gynäkologischen Praxis.
Gyn. Endokrinologie, Springer Verlag 2008
6:82-86
Seidlová-Wuttke D,
Jarry H,
Jäger Y,
Wuttke W.
Bone development in female rats maintained with soy-free or soy-containing food
as determined by computer-assisted tomography and serum bone markers.
J Bone Miner Metab. 2008;26(4):321-7.
Sehmisch, Stephan; Hammer, Frauke; Christoffel, Julie; Seidlova-Wuttke, Dana;
Tezval Mohammed;
Wuttke,
Wolfgang; Stürmer, Klaus Michael; Stürmer, Ewa Klara
Comparison of the Phytohormone Genistein, Resveratrol and 8-Prenylnaringenin as
Agents for Preventing Osteoporosis.
Planta Med.
2008 Jun;74(8):794-801.
D.
Seidlová-Wuttke,
H. Jarry, Y.
Jäger, W. Wuttke
Bone development in the female rats kept under soy-containing food as determined
by computer tomographiy and by serum bone markers. Journal of Bone and
Mineral Metabolism 2008, Vol. 26, No.4
Rachón
D, Menche A, Vortherms T, Seidlová-Wuttke D, Wuttke W
Effects of dietary equol administration on the mammary gland in ovariectomized
Sprague-Da3wley rats. Menopause. 2008 Mar-Apr; 15(2):340-5
Thelen P, Peter T,
Hütermund A, Kaulfuß S, Seidlová-Wuttke D, Wuttke W, Ringert RH, Seseke F
Phytoestrogens from Belamcanda chinensis regulate the expression of steroid
receptors and related cofactors in LNCaP prostate cancer cells. BJU Int,
2007, 100(1): 199-203
G.
Rimoldi, J. Christoffel, D. Seidlová-Wuttke, H. Jarry, W. Wuttke
Effects
of Chronic Genistein Treatment in Mammary Gland, Uterus and Vagina
Environmental
health Perspectives, Dezember 2007, Vol. 115, Supplement 1, P 62-68
Rachoń D,
Seidlová-Wuttke D,
Vortherms T,
Wuttke W.
Effects
of dietary equol administration on ovariectomy induced bone loss in
Sprague-Dawley rats.
Maturitas.
2007 Nov 20;58(3):308-15. Epub 2007 Oct 24.
Rachón
D, Vortherms T, Seidlová-Wuttke D, Wuttke W
Dietary daidzein and puerarin do not affect pituitary LH expression but exert
uteritropic effects in ovariectomized rats. Maturitas. 2007 Jun 20;
57(2):161-70. Epub 2007 Jan 26
Rachon,
D., Vortherms, T., Seidlová-Wuttke, D., Wuttke, W.
Effects of dietary equol on body weight gain, intra-abdominal fat
accumulation, plasma lipids and glucose tolerance in ovariectomized
Sprague-Dawley rats, Menopause 14, (5), 1-8, 2007, PMID: 17414092
Rachon
D, Vortherms T, Seidlová-Wuttke D, Menche A, Wuttke W
Uterotropic effects of dietary equol administration in ovariectomized
Sprague-Dawley rats. Climacteric, 10(5): 416-26, 2007
Jarry
H, Strromeier S, Wuttke W, Nahrstedt A
Petasphenone, a phenol isolated from Cimicifuga racemosa, in vitro inhibits
proliferation of the human prostate cancer cell line LNCaP. Planta Med, 73(2):
184-7, 2007
Wuttke,
W., Jarry, H., Seidlová-Wuttke, D.
Cimicifuga racemosa extract for the treatment of climacteric complaints, J
Endoc Reprod (India), 10, 2:106-110, 2006
Paul
Thelen, F. Seseke, RH Ringert, Wolfgang Wuttke, Dana Seidlova-Wuttke,
Pharmacological potential of phytoestrogens in the treatment of prostate cancer, Urologie A, 45(2): 195-6, 197-201, 2006
Jarry, H.,
Thelen, P., Christoffel, V., Spengler, B., Wuttke, W.
Cimicifuga racemosa extract BNO 1055 inhibits proliferation of the human
prostate cancer cell line LNCaP. Phytomedicine, in press, 2005
Seidlová-Wuttke, H. Jarry, D., Pitzel, L., Wuttke, W.
Effects of estradiol-17ß, testosterone and a Black Cohosh preparation on bone
and prostate in orchidectomized rats. Maturitas, in press, 2005
Seidlová-Wuttke, H. Jarry, D., Pitzel, L., Wuttke, W.
Effects of estradiol-17ß, testosterone and a Black Cohosh preparation on bone
and prostate in orchidectomized rats. Maturitas, in press, 2004
Seidlová-Wuttke, D., Hesse, O., Jarry, H., Rimoldi, G., Thelen, P., Christoffel,
V., W. Wuttke
Belamcanda chinensis and the thereof purified tectorigenin have selective
estrogen receptor modulator activities. Phytomedicine 11.392-403, 2004
Thelen, P., Wuttke, W.,
Jarry, H., Grzmil M, Ringert, R-H.
Inhibition of telomerase activity and secretion of prostate-specific antigen by
silibinin in prostate cancer cells. J Urol 171:1934-1938,
2004
Thelen, P.,
Jarry, H., Ringert, R-H., Wuttke, W.
Silibinin down-regulates prostate epithelium-derived Ets transcription factor in
LNCaP prostate cancer cells. Planta Med 70:397-400, 2004
Wuttke, W.,
Jarry, H., Christoffel, V., Spengler, B., Seidlová.Wuttke, D.
Chaste tree (Vitex Agnus-castus) – Pharmacology and clinical indications.
Phytomedicine, 10:348-357, 2003
Jarry, H.,
Metten, M., Wuttke, W., Spengler, B., Christoffel, V.
In vitro effects of the Cimicifuga racemosa extract BNO 1055.
Maturitas 44: S31-38, 2003
Jarry, H.,
Spengler, B., Porzel, A., Schmidt, J., Wuttke, W., Christoffel, V.
Evidence for estrogen receptor ß-selective activity of Vitex Agnus castus
and isolated flavones. Planta Medica 69: 945-947, 2003
Seidlová-Wuttke, D., Becker, T., Christoffel, V., Jarry, H., Wuttke, W.
Silymarin is a selective estrogen receptor ß (ERß) agonist and has estrogenic
effects in the metaphysis of the femur but no or antiestrogenic effects in the
uterus of ovariectomiezed (ovx) rats. J Steroid Biochem Mol Biol
86:179-188, 2003
Seidlová-Wuttke, D., Hesse, O., Jarry, H., Christoffel, V., Spengler, B.,
Becker, T., Wuttke, W.
Evidence for selective estrogen receptor modulator activity in a black cohosh
(Cimicifuga racemosa) extract: comparison with estradiol-17ß. Eur J
Endocrinol 149:351-362, 2003
Seidlová-Wuttke, D., Jarry, H., Becker, T., Christoffel, V., Wuttke, W.
Pharmacology of Cimicifuga racemosa extract BNO 1055 in rats: bone, fat
and uterus. Maturitas 44:S39-50, 2003
Wuttke, W.,
Seidlová-Wuttke, D., Gorkow, C..
The Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind
placebo-controlled study: effects on menopause symptoms and bone markers.
Maturitas 44:S67-77, 2003
Wuttke, W.,
Jarry, H., Becker, T., Schultens, A., Christoffel, V., Gorkow, C.,
Seidlová-Wuttke, D.
Phytoestrogens: Endocrine disrupters or replacement for hormone replacement
therapy? Maturitas 44:S9-20, 2003
Wuttke, W.,
Seidlová-Wuttke, D., Balzer, I., Becker, T., Heiden, I., Jarry, H., Christoffel,
V.
Phytoestrogens: dangerous drugs or soft hormones? In: Menopause:
The State of the Art – in research and management. Ed. H.P.G. Schneider,
Parthenon Publishing, pp. 295-306, 2003
Wuttke, W.,
Jarry, H., Westphalen, S., Christoffel, V., Seidlová-Wuttke, D.
Phytoestrogens for hormone replacement therapy? J Steroid Biochem Mol Biol
83:1-5, 2002
Neuroendokrinologie
Nicolas
Lang1,2, Holger Rothkegel1,2, Heidi Reiber2,
Alkomiet Hasan2, Elke Sueske2, Frithjof Tergau2,
Hannelore Ehrenreich4, Wolfgang Wuttke3, Walter Paulus2
Circadian changes of GABA-mediated cortical inhibition. subm to Biolog Psych,
4/2010
T.A. Roepke1*,
M.A. Bosch1*, E.A. Rick1, B. Lee4, E.J. Wagner4, D. Seidlova-Wuttke5, W.
Wuttke512 , T.S.Scanlan1, O.K. Rønnekleiv1,2,3 and M.J. Kelly1
Contribution of the membrane estrogen receptor to the estrogenic regulation of
bodytemperature and energy homeostasis. Endocrinology 2010
Claire
J Herzog, Boldizsár Czéh, Silke Corbach, Wolfgang Wuttke,
Olaf Schulte-Herbrüggen, Rainer Hellweg, Gabriele Flügge and Eberhard Fuchs
Long term social instability stress in female rats: Effect on behaviour, body
temperature and endocrine parameters. Neuroscience, 2008 accepted
Böttner
M, Christoffel J, Wuttke W
Effects of
long-term treatment with 8-prenylnaringenin and oral estradiol on the GH-IGF-1
axis and lipid metabolism in rats.
J Endocrinol.
2008 Aug;198(2):395-401
Rachon
D, Vortherms T, Seidlova-Wuttke D, Wuttke W,
Effects of dietary equol on the pituitary of the ovariectomized rats, Hormone
and Metabolic Research, 39:256-61, 2007, PMID: 17447162
Happe
S, Tings T, Koch W, Welsch J, Helmschmied K, Baier PC, Meller J, Wuttke W,
Paulus W, Tatsch K, Trenkwalder C
Growth-hormone response in low-dose apomorphine test correlates with
nigrostriatal dopmanine transporter binding in patients with Parkinson’s
disease. J Neural Transm, 114(5): 589-94, 2007
Happe,
S, Bachmann CG, Helmschmied K, Neubert, K, Wuttke W, Paulus W, Trenkwalder C
Growth hormone response to low-dose apomorphine in restless legs syndrome.
Growth Horm IGF Res. 17(4): 323-327, 2007
Böttner
M, Leonhardt S, Wuttke W, Jarry H,
Changes of expression of genes related to the activity of the
gonadotropin-releasing hormone pulse generator in young versus middle-aged male
rats. J Neuroendocrinol, 19(10): 779-87
Martina
Böttner, Wolfgang Wuttke
Chronic treatment with physiological doses of estradiol affects the GH-IGF-I
axis and fat metabolism in young and middled-aged ovariectomized rats,
Biogerontology 7:91-100, 2006
Svenja
Happe, Cornelius Bachmann, Kathrin Helmschmied, Karin Neubert, Wolfgang Wuttke,
Walter Paulus, Claudia Trenkwalder,
Lack of evidence for increased hypothalamic dopaminergic receptor sensitivity in
restless legs syndrome, submitted to Neurology, 2006
Martina
Böttner, Wolfgang Wuttke
Chronic treatment with low doses of estradiol affects the GH-IGF-I axis and
liver metabolism in young and middled-aged ovariectomized rats,
Biogerontology 6:261-269, 2005
Roth, C.,
Hegemann, F., Hildebrandt, J., Balzer, I., Witt, A., Wuttke, W., Jarry, H.
Pituitary and gonadal efects of GnRH (gonadotropin releasing hormone) analogues
in two peripubertal female rat models. Pediatr Res 55:126-133, 2004
Jarry, H.,
Metten, M., Gamer, A.O., Wuttke, W.
Effects of 5-day styrene inhalation on serum prolactin and dopamine levels and
on hypothalamic and striatal catecholamine concentrations in male rats.
Archives in Toxicology 76:657-663, 2002
Moguilevsky JA,
Wuttke W.
Changes in the control of gonadotrophin
secretion by neurotransmitters during sexual development in rats. Exp Clin Endocrinol Diabetes.
2001;109(4):188-95. Review.
Roth C, Schricker M, Lakomek M, Strege
A, Heiden I, Luft H, Munzel U, Wuttke W, Jarry H.
Autoregulation of the gonadotropin-releasing hormone (GnRH) system during
puberty: effects of antagonistic versus agonistic GnRH analogs in a female rat
model.
J Endocrinol. 2001 May;169(2):361-71.
Han J, Seong JY, Kim
K, Wuttke W, Jarry H.
Analysis of exonic splicing enhancers in the mouse
gonadotropin-releasing hormone (GnRH) gene. Mol Cell
Endocrinol. 2001 Feb 28;173(1-2):157-66.
Roth C, Schmidberger
H, Lakomek M, Witt O, Wuttke W, Jarry H.
Reduction of gamma-aminobutyric acid-ergic
neurotransmission as a putative mechanism of radiation induced activation of the
gonadotropin releasing-hormone-pulse generator leading to precocious puberty in
female rats. Neurosci Lett. 2001 Jan 5;297(1):45-8.
Roth C, Leonhardt S, Seidel C, Luft H, Wuttke W, Jarry H.
Comparative
analysis of different puberty inhibiting mechanisms of two GnRH agonists and the
GnRH antagonist cetrorelix using a female rat model. Pediatr Res. 2000
Oct;48(4):468-74.
Ovarforschung
Wuttke, W., Hinney, B.
Störung der weiblichen Gonaden, Medizinische Therapie 2007/2008, 3. Auflage, S.
690-716, 2007
Wuttke W, Pitzel L,
Seidlova-Wuttke D, Hinney B.
LH pulses and the corpus
luteum: the luteal phase deficiency LPD). Vitam Horm.
2001;63:131-58. Review.
Pitzel L, Ludemann S,
Wuttke W.
Secretion and gene expression of metalloproteinases and gene
expression of their inhibitors in porcine corpora lutea at different stages of
the luteal phase. Biol Reprod. 2000 May;62(5):1121-7.
Hirsch B, Knoke I,
Leonhardt S, Pitzel L, Jarry H, Wuttke W.
Stimulation of
matrix-metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 gene
expression in rats by the preovulatory prolactin peak. Eur J Endocrinol. 1999
Jun;140(6):583-9.
Wuttke W, Spiess S,
Knoke I, Pitzel L, Leonhardt S, Jarry H.
Synergistic effects of prostaglandin F2alpha and tumor
necrosis factor to induce luteolysis in the pig. Biol Reprod. 1998
May;58(5):1310-5.
Klinische Forschung
Wuttke W, Jarry
H, Seidlova-Wuttke D.
(2009): Plant-derived alternative
treatments for the aging male: facts and myths. Aging male . Epub ahead of print
W. Wuttke.
Phytoestrogens: endocrine disrupters or replacement for hormone replacement
therapy? Maturitas 61 (2008) 159-170
Wuttke W.
Food supplementation products. Soya: more risks than
benefits? MMW Fortschr Med. 2008 Jan 17;150(1-2):21. German.
W. Wuttke.
Kontra. Gynäkologie und Geburtshilfe 4-2008
Wolfgang Wuttke.
Soja: mehr Risiken als Nutzen? Gyn. und Geburtshilfe, 1-2008
W. Wuttke.
Nahrungsergänzungsmittel; Soja: mehr Risiken als Nutzen? MMW, Fortschritte der
Medizin, Nr. 1-2/2008 (150. Jg.)
Thelen P,
Burfeind P, Schweyer S, Scharf JG, Wuttke W, Ringert RH.
Molecular principles of alternative approaches for hormone-refractory prostate
cancer. Urologie, 2007 46(9): 1271-4
Wuttke, W.,
Jarry, H., Seidlova´-Wuttke, D.
Isoflavones—Safe food additives or dangerous drugs?, Ageing Research Reviews 6,
150–188, 2007, Epub ahead of print
Wuttke W, Jarry
H, Seidlová-Wuttke D.
(2006): Cimicifuga racemosa extract for
the treatment of climacteric complaints. J Endoc Reprod
(India), 10, 2,106-110.
Wuttke W,
Rimoldi G, Christoffel J, Seidlová-Wuttke D.
(2006): Plant extracts for the treatment
of menopausal women: safe? Maturitas supplement, 55S, 92-100.
Seidlová-Wuttke
D, Pitzel L, Thelen P, Wuttke W.
(2006): Inhibition of 5a-reductase in the
rat prostate by Cimicifuga racemosa. Maturitas Supplement, 55S, 75-82.
Thelen P,
Seseke F, Ringert RH, Wuttke W, Seidlova-Wuttke D.
(2006):
Pharmacological potential of phytoestrogens in the treatment of prostate cancer,
Urologie , 45(2), 195-6.
W. Wuttke und D. Seidlová-Wuttke
Phytoöstrogene und Altern. Jubiläumsband: EinVierteljahrhundert Frauenheilkunde
und Geburtshilfe aus Münsteraner Sicht, August 2004, Münster
Boschitsch E,
Skarabis H, Wuttke W, Heithecker R.
The acceptability of a novel oral contraceptive
containing drospirenone and its effect on well-being. Eur J Contracept Reprod
Health Care. 2000 Dec;5 Suppl 3:34-40.
Blode H, Wuttke W, Loock W, Roll G, Heithecker R.
A 1-year pharmacokinetic investigation of a novel oral
contraceptive containing drospirenone in healthy female volunteers. Eur J
Contracept Reprod Health Care. 2000 Dec;5(4):256-64.
Huber J, Foidart JM, Wuttke W, Merki-Feld GS, The HS, Gerlinger
C, Schellschmidt I, Heithecker R.
Efficacy and tolerability
of a monophasic oral contraceptive containing ethinylestradiol and drospirenone.
Eur J Contracept Reprod Health Care. 2000 Mar;5(1):25-34.
Rosenbaum P, Schmidt W, Helmerhorst FM, Wuttke W, Rossmanith W,
Freundl F, Thomas K, Grillo M, Wolf A, Heithecker R.
Inhibition of ovulation by
a novel progestogen (drospirenone) alone or in combination with
ethinylestradiol. Eur J Contracept Reprod Health Care. 2000 Mar;5(1):16-24.
Osteoporoseforschung
Kapur P, Wuttke
W, Seidlova-Wuttke D.
(2010): Beneficial effects of ß-Ecdysone
on joint, epiphyseal cartilage tissue and trabecular bone in ovarectomized rats.
Phytomedicine, 17, 350-355
Sehmisch S,
Dullin C, Zaroban A, Tezval M, Rack T, Schmelz U, Seidlova-Wuttke D, Dunkelberg
H, Wuttke W, Marten K, Stuermer KM, Stuermer EK
.
(2009): The use of flat panel volumetric
computed tomography
(fpVCT) in osteoporosis research.
Academic Radiology, 16(4), 394-400.
Sehmisch S,
Boeckhoff J, Wille J, Seidlova-Wuttke D, Rack T, Tezval M, Wuttke W, Stuermer
KM, Stuermer EK (2009):
Vitex agnus castus as
prophylaxis for osteopenia after orchidectomy in rats compared with estradiol
and testosterone supplementation. Phytother Res., 23,851-858.
Sehmisch S,
Dullin C, Zaroban A, Tezval M, Rack T, Schmelz U, Seidlova-Wuttke D, Dunkelberg
H, Wuttke W, Marten K, Stuermer KM, Stuermer EK
.
(2009): The use of flat panel volumetric
computed tomography
(fpVCT) in osteoporosis research.
Academic Radiology, 16(4), 394-400
Sehmisch S, Hammer F, Christoffel J, Seidlová-Wuttke D, Tezval M, Wuttke W,
Stürmer KM, Stürmer EK
(2009): Comparison of the Phytohormone
Genistein, Resveratrol and 8-Prenylnaringenin as Agents for Preventing
Osteoporosis. Planta Medica, 74(8),
794-801.
Tezval M,
Sehmisch S, Seidlová-Wuttke D, Rack T, Kolios L, Wuttke W, Stuermer KM, Stuermer
EK.
(2010): Changes in the Histomorphometric and Biomechanical Properties of the
Proximal Femur of Ovariectomized Rat after Treatment with the Phytoestrogens
Genistein and Equol. Planta Medica, 76(3):235-40.
Sehmisch S,
Erren M, Rack T, Tezval M, Seidlova-Wuttke D, Richter J, Wuttke W. Stürmer K,
Stürmer EK.
(2009): Short-Term Effects of Parathyroid Hormone on Rat Lumbar
Vertebrae. Spine, 34(19), 2014-21.
Stuermer EK,
Sehmisch S, Tezval M, Tezval H, Rack T, Boekhoff J, Wuttke W, Hermann TR,
Seidlova-Wuttke D, Stuermer KM.
(2009): Effect of testosterone and estrogen
replacement on the microstructure and biomechanics of metaphyseal osteoporotic
bones in orchidectomized male rats. World J Urol, 27(4), 547-555
Seidlová-Wuttke
D,
Jarry H,
Jäger Y, Wuttke W.
(2008): Bone development in the female
rats kept under soy-containing food as determined by computer tomography and by
serum bone markers. Journal of Bone and Mineral Metabolism., 26(4),
321-327.
Seidlová-Wuttke D,
Schlumbohm C,
Jarry H,
Dullin C,
Wuttke W.
Orchidectomized (orx) marmoset (Callithrix jacchus) as a model to study the
development of osteopenia/osteoporosis.
Am J Primatol. 2008
Mar;70(3):294-300.
S. Seidlová-Wuttke, K. Prelle, K.-H. Fritzemeier, W. Wuttke
Effects of estrogen receptor alpha- and beta-selective substances in the
metaphysis of the tibia and on serum parameters of bone and fat tissue
metabolism of ovariectomized rats.
Bone. 2008
Nov;43(5):849-55
Priya Kapur, H. Jarry, B.N Pereira, Dana Seidlová-Wuttke
Evaluation of the antiosteoporotic potential of Tinospora cordifolia in female
rats. Maturitas 59 (2008) 329-38
Sehmisch S, dullin C, Zaroban A, Tezval M, Rack T, Schmelz U, Seidlova-Wuttke D,
Dunkelberg H, Wuttke E, Marten K, Stuermer KM, Stuermer EK.
The use of flat panel volumetric computed tomography (fpVCT) in osteoporosis
research. Acad Radiology 2008 Apr; 16(4):394-400
Sehmisch S, Boeckhoff J, Wille J, Seidlova-Wuttke D, Rack T, Tezval M, Wuttke W,
Stuermer KM, Stuermer EK
Vitex agnus castus as
prophylaxis for osteopenia after orchidectomy in rats compared with estradiol
and testosterone supplementation. Phytother Res. 2008 Dec 23.
Stuermer EK, Sehmisch S, Rack T, Wenda E, Seidlova-Wuttke D, Tezval M, Wuttke W,
Frosch KH, Stuermer KM.
Estrogen and raloxifene
improve metaphyseal fracture healing in the early phase of osteoporosis. A new
fracture-healing model at the tibia in rat. Langenbecks
Arch Surg.
2008 Dec 2.
Stürmer
EK., Seidlová-Wuttke D, Sehmisch S, Rack T, Wille J, Frosch KH, Wuttke W,
Stürmer KM.
(2006): A standardized bending and
breaking test for the normal and osteoporotic metaphyseal tibia of the rat.
Effect of estrogen, testosterone and raloxifene.
J Bone Miner
Res, 21, 89-96.
|